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Pain Management

Now Offering Endura-Kit™ Injectable For Postsurgical Non-Opioid Pain Management. Brought to you by InfuBLOCK™.

Endura-Kit™ features a patented local anesthetic compound, Enduracaine™, consisting of three non-opioid drugs: Tetracaine, Lidocaine and Epinephrine, to provide non-opioid pain control for enhanced recovery after surgery.

Endura-KitTM may be suitable for a variety of surgical procedures for longer-acting local incisional infiltration as well as for longer-acting regional anesthesia with peripheral nerve blocks and fascial plane blocks.

The low toxicity of this combination, due to the dilute concentration of the components, allows for higher volume dosing for volume/plane blocks to ensure full coverage of affected nerves.2,3

Pain-Control Applications: Use for incisional infiltration, major and minor regional nerve blocks, soft tissue infiltration, subcutaneous, epidural and intra-articular injection.

What is Endura-Kit™ Injectable?
(Tetracaine 0.2%/Lidocaine 0.4%, Epinephrine 1:1000)

  • Endura-Kit™ is a local anesthesia compound that offers a solution for non-opioid pain relief. Endura-Kit™ provides long acting, safe pain relief for post-operative care.
  • Endura-Kit™ contains two components, which, when combined, mixes into a preservative-free, patented local anesthetic compound.
  • Endura-Kit™ consists of one preloaded Luer-Lock syringe with an 18g mixing needle containing 0.2mL of Epinephrine 1:1000, and one vial containing 50mL of Tetracaine and Lidocaine. Combining these two components results in a solution of 0.2% Tetracaine/0.4% Lidocaine with Epinephrine 1:250,000.
  • The maximum recommended dose is 1.5mL/kg IBW.1
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Benefits

  • Opioid Free Pain Relief
  • A Versatile Post-Operative Pain Management Solution
  • Low-Toxicity Formula
  • Helps Minimize Opioid Related Side Effects
  • Potential Reduced Need for Narcotic Prescriptions
  • Long Lasting Localized Pain Relief

Cost Effective and Available Throughout the U.S. to Improve the Quality of Life for All Patients

Increase patients' level of comfort with fewer opioid related side effects

Enhanced Recovery After Surgery

Endura-Kit™ Injectable addresses the demand for non-opioid pain control after surgery by providing adequate pain relief to increase patients’ comfort level with fewer opioid related side effects.

Endura-KitTM includes:

    One Pre-Loaded Luer-Lock Syringe Containing 0.2mL of Preservative-Free Epinephrine 1:1000, USP (0.2mg/0.2mL)

    One Sterile Injection Vial Containing 50mL Preservative-Free 0.4% Lidocaine HCI with 0.2% Tetracaine HCI

Combining these two components results in a solution of 0.2% Tetracaine/0.4% Lidocaine with Epinephrine 1:250,000. A maximum recommended dose is 1.5mL/kg IBW.

  • Alcohol Prep Pad
  • 18G 1” Blunt Needle
  • Green Transfer Label Sticker
  • Directions for Use Insert

Download Literature

Disclaimer:
Medications can only be ordered by health care providers when it is determined the product is clinically significant over other commercially available products. Endura-Kit™ is not recommended for obstetric, spinal topical or intravenous use. This product is an off-label use of two long available and very safe anesthetics. Endura-Kit™ has not been evaluated or approved by the FDA. Because Enduracaine™ is made from a combination of currently approved USP products, its use before specific FDA approval of a new drug application is safe and acceptable.
 References:
1 Local Anesthetics. Ian K McLeod, MD; Chief Editor: Arlen D Meyers, MD, MBA et al. Updated: Mar 18, 2015. http://emedicine.medscape.com/article/873879-overview#a5. 2 Epinephrine prolongs duration of subcutaneous infiltration of local anesthesia in a dose-related manner. Correlation with magnitude of vasoconstriction. S Liu, R L Carpenter, A A Chiu, T J McGill, S A Mantell. Regional Anesth. Sep-Oct 1995; 20(5):378-84. 3 Laparoscopic-Guided Transversus Abdominis Plane Block for Colorectal Surgery, Joanne Favuzza, D.O. • Conor P. Delaney, M.D. Dis Colon Rectum 2013; 56: 389–391DOI: 10.1097/DCR.0b013e318280549b © The ASCRS 2013. 4 The Opioid Epidemic: By the Numbers. http://www.hhs.gov/opioids/. 5 New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults. Chad M. Brummett, MD, et al. JAMA Surg. Published online April 12, 2017. doi:10.1001/jamasurg.2017.0504 6 Benefit and risks of local anesthetics in infants and children. Gunter JB. Paediatric Drugs. 2002;4(10):649-72. 7 Evidence-based practice supports adopting ERAS protocols. OR Manager Vol. 33 No. 5 May 2017. Brydges G. 8 On the Mechanism by Which Epinephrine Potentiates Lidocaine’s Peripheral Nerve Block. Catherine J. Sinnott, B.A.; Lawrence P. Cogswell, Ph.D.; Anthony Johnson, B.S.; Gary R. Strichartz, Ph.D. Anesthesiology January 2003, Vol. 98, 181–188. https://doi.org/10.1097/00000542-200301000-00028. 9 Anesthesiology. 1981 Mar; 54(3):177-81. Mixtures of local anesthetics are no more toxic than the parent drugs. de Jong RH, Bonin JD.
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